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SLEEP
A systematic review of 30 longitudinal MRI studies found that CPAP therapy in obstructive sleep apnea (OSA) may be associated with structural, functional, vascular, and metabolic brain changes. However, the evidence remains heterogeneous, largely exploratory, and insufficient to support routine MRI monitoring of treatment response.
Neurology September 9th 2026
Annals of Internal Medicine
The OSPREY trial puts proximal hypoglossal nerve stimulation on the map for moderate-to-severe OSA, with strong short-term numbers and the limitations a small unblinded RCT carries.
Neurology April 30th 2026
Medical Professionals Reference (MPR)
“With two large phase 3 studies now demonstrating a consistent and significant efficacy profile for AD109, we are closer to delivering the first oral pharmacotherapy for over 80 million US adults with OSA.”
Family Medicine/General Practice August 20th 2025