Articles related to Urology

A randomized noninferiority trial involving 648 men with MRI-visible prostate lesions found that cognitive fusion biopsy achieved clinically significant prostate cancer detection rates similar to software-based fusion biopsy. Subgroup analyses suggested body mass index may influence the relative performance of each approach.

A two-year analysis of 12,670 screened men found that the Stockholm3 risk model detected more clinically significant prostate cancers than PSA testing alone, primarily through fewer false-negative results. The findings suggest improved screening discrimination, although follow-up remains limited to two years.

The Department of Defense announced annual testosterone-deficiency screening for service members aged 30 years and older, with optional testing for younger personnel. Clinicians have questioned whether broad population screening aligns with established diagnostic recommendations for hypogonadism.

A repeat PSMA PET/CT scan detected recurrent disease in more than half of prostate cancer patients whose initial scan was negative. Findings altered management in nearly half of patients, particularly those with oligometastatic recurrence.

A nationwide surveillance study identified widespread community reservoirs of multidrug-resistant Klebsiella pneumoniae associated with recurrent urinary tract infections and antibiotic resistance.

A multivariable screening test detects 90% of clinically significant prostate cancers vs 74% with PSA alone, suggesting PSA thresholds may miss aggressive disease despite similar false-positive rates.