In this target trial emulation involving nearly 44,000 patients with primary hyperparathyroidism (PHPT), similar declines in kidney function at 5 and 10 years were seen in patients managed with parathyroidectomy and in those managed nonoperatively. Thus, in this study, parathyroidectomy had no effect on long-term kidney function in older adults with PHPT.

This summary of a recent French study highlights that patients enabled to infuse apomorphine at home improved QoL more quickly and became more autonomous in managing the device compared with a hospital infusion group. The findings could be helpful to patients who would benefit from continuous subcutaneous apomorphine infusion (CSAI) but are deterred “by the wait for an appointment and the length of the subsequent hospital stay, as well as the physical distance from the nearest specialist center.”

In a study originally published in Multiple Sclerosis and Related Disorders, alemtuzumab infusion resulted in significantly improved MS-COG scores in the patients evaluated after 12 months, with scores improving from an initial mean of -0.36, to 0.61.

The authors describe the case as well as the science around TRD and ketamine-assisted psychotherapy (KAP), explore the patient’s patterns of self-criticism and its impact on his depression and help-seeking, and their approach to KAP. This case report and review represents an “excellent example of how using different therapeutic frameworks is essential in the conceptualization and treatment of TRD.”

Diagnosing – and treating – ADHD in adults is not difficult and can be life-changing, with patients noting improvements in relationships, functional ability, and overall quality of life.

The video features an interview with Dr. Jason Mouabbi, a surgical oncologist, who discusses the management of invasive lobular carcinoma (ILC), a type of breast cancer that is less common than other types. He explains that ILC is more challenging to diagnose than other breast cancers because it does not form a lump, but rather spreads in a linear fashion throughout the breast tissue. Dr. Mouabbi highlights the importance of early detection and screening for ILC. He then discusses the treatment options for ILC, which may include surgery, radiation therapy, and hormone therapy. He emphasizes the need for personalized treatment plans for each patient based on their specific case and individual needs. Dr. Mouabbi also talks about the potential role of neoadjuvant therapy in improving outcomes for patients with ILC. Overall, the video provides valuable insights into the management of ILC and highlights the importance of early detection and personalized treatment plans.