Articles related to OPTIC NERVE DISORDERS

A systematic review and meta-analysis linked plasma exchange with high recovery rates in MOGAD attacks, especially optic neuritis. Included studies were observational and could not isolate PLEX effects.

A Swedish register-based cohort associated GLP-1 receptor agonist use with higher relative risk of anterior ischemic optic neuropathy. Absolute event rates were low, and findings attenuated after diabetes-severity controls.

OCT, B-scan ultrasound, and ultrasound biomicroscopy identified distinct structural signatures across hypotony sequelae including maculopathy, choroidal detachment, and cyclodialysis cleft in cases where slit-lamp examination and indirect ophthalmoscopy alone proved insufficient.

Peripapillary hyperreflective ovoid mass-like structures showed no significant correlation with intracranial pressure levels in a cross-sectional cohort of 54 patients with idiopathic intracranial hypertension, suggesting anatomic rather than pressure-driven origins.

A retinal specialist reviewing GLP-1 ocular safety evidence at the Retina World Congress concluded that current data do not support withholding therapy based on ocular risk alone, while recommending baseline retinal examination and closer monitoring in patients with preexisting severe diabetic retinopathy.

A retrospective cohort study of 349,168 propensity-matched patients with diabetes found a hazard ratio of 2.22 for nonarteritic anterior ischemic optic neuropathy among semaglutide users compared with non-GLP-1 RA antidiabetic therapy users, with elevated risk emerging at two years and persisting through four years of follow-up.