Articles related to Family Medicine/General Practice

A malpractice case involving missed postoperative decline highlights failures to act on evolving infection and organ dysfunction trends following abdominal surgery.

BCG vaccination increased immune responsiveness without inflammatory activation and shifted beta-amyloid patterns in a small mechanistic study of older adults.

The FDA has begun reviewing generic tirzepatide applications as global competition accelerates, despite US patent protections limiting near-term availability.

A multi-fiber formulation improved bowel frequency and stool consistency in adults with functional constipation in a short-term study evaluating combined fiber mechanisms.

A physician associate in an understaffed emergency department diagnosed a patient’s severe back pain as sciatica after a CT scan read as normal. Five days later, a different clinician identified a perirectal abscess that had already progressed to require multiple surgeries.

The FDA approved cefepime-zidebactam (Zaynich) for complicated UTI and pyelonephritis caused by susceptible gram-negative organisms. Approval followed phase 3 trial data showing higher rates of symptom and microbiologic resolution compared with meropenem in hospitalized adults.