Articles related to GUIDELINES/RECOMMENDATIONS

An updated review of multiple myeloma management highlights revised high-risk definitions, anti-CD38-based quadruplet induction regimens, evolving maintenance strategies, and increasing use of CAR-T and bispecific immunotherapies across the disease continuum.

The American Gastroenterological Association issued nine best practice statements on colorectal and esophageal surveillance in older adults. Recommendations emphasize individualized decisions, life expectancy, treatment candidacy, procedural risks, and patient preferences.

Emerging evidence suggests the sodium-to-potassium ratio may better reflect cardiovascular risk than sodium intake alone. Experts emphasized that increasing dietary potassium alongside sodium reduction may support blood pressure control, while acknowledging important safety considerations for select patient populations.

The FDA approved Freenome’s SimpleScreen CRC blood test for colorectal cancer screening in average-risk adults. Clinical study results showed the test detected roughly 80% of colorectal cancers, though current guidelines continue to favor colonoscopy and stool-based screening options.

Pediatric hearing loss care has shifted from physiologic detection and rehabilitation toward genetic diagnosis, prognostic counseling, and emerging targeted therapies. Advances in screening, cochlear implantation, and genetic testing have expanded etiologic evaluation, while therapeutic applications remain in early development.

The American Thoracic Society updated guidance for childhood interstitial lung disease in infants, emphasizing genetic testing, chest imaging, biopsy indications, and transplant referral. Recommendations formalize evaluation priorities for rare pediatric lung disorders.