Articles related to Obstetrics & Gynecology

Female mice recovering from a single ketamine exposure demonstrated microglia-driven neuroplasticity through FKBP51 activation, while male mice did not. The findings identify a sex-specific biologic pathway in a preclinical model, and human relevance remains unconfirmed.

Women presenting with acute myocardial infarction often report chest pain alongside additional symptoms such as dyspnea, nausea, fatigue, or jaw pain. Persistent diagnostic disparities continue to contribute to delays in recognition and treatment, particularly among younger women.

A national analysis found that clinical obesity was present in more than one-quarter of adults with normal BMI values. The findings highlight limitations of BMI alone for identifying excess adiposity and obesity-related health risk.

A Phase 2 trial of luvesilocin reported rapid reductions in postpartum depression symptoms, with most treated participants reaching remission within seven days. The investigational psychedelic has received FDA Breakthrough Therapy designation, but Phase 3 confirmation remains pending.

Pregnancy is well tolerated for many women with congenital heart disease, but outcomes vary substantially by underlying lesion and clinical characteristics. Current guidance emphasizes multidisciplinary counseling, structured risk assessment, and individualized management before conception.

A large ECHO Cohort analysis associated several pregnancy urinary chemical biomarkers with modest shifts in gestational age and fetal growth measures. The observational findings did not establish causality.