Articles related to CLINICAL STUDY

This comprehensive study sheds light on the lasting cognitive impacts of COVID-19, revealing that post-infection cognitive deficits can endure beyond a year, significantly affecting memory and executive functions. These findings underscore the importance of long-term cognitive monitoring in COVID-19 survivors.

This longitudinal study offers an unprecedented look at the temporal changes in CSF and imaging biomarkers over two decades, providing clinicians with a detailed timeline of biomarker alterations that precede the clinical onset of Alzheimer’s disease, thereby paving the way for potential early diagnostic and therapeutic strategies.

This study illuminates the potential of preoperative circulating tumor DNA to redefine the approach to treating high-risk upper tract urothelial carcinoma, offering a nuanced tool for assessing the necessity of neoadjuvant chemotherapy and tailoring patient care.

In a recent randomized trial comparing radical and simple hysterectomy in patients with low-risk cervical cancer, findings demonstrated that simple hysterectomy was not inferior in preventing pelvic recurrence at 3 years and offered a significant reduction in postoperative urinary complications.

This study underscores the importance of refining and adhering to outpatient management protocols for low-risk acute pulmonary embolism patients. Despite the proven safety and effectiveness of such approaches, only one third of eligible patients were discharged for outpatient care between 2012 and 2020, indicating a significant gap in practice.

Physicians should be acutely aware of the heightened risk of neuroinvasive arboviral infections in patients treated with rituximab, necessitating a shift towards molecular diagnostic testing for timely and accurate detection.