Articles related to CLINICAL STUDY

Frontal tau accumulation was associated with disrupted deep-sleep slow waves and poorer episodic memory performance in older adults, offering a potential physiological link between Alzheimer’s-related pathology and age-related memory decline.

Muscle ultrasound measurements obtained before and after exercise distinguished patients with generalized myasthenia gravis from healthy controls in a small case-control study, suggesting a potential imaging approach for assessing fatigability.

In a specialty-clinic cohort of 2,329 adults with Neuro-PASC, females reported more neurologic symptoms, greater fatigue, and, among nonhospitalized patients, poorer attention than males approximately 16 months after symptom onset.

Prebiopsy prostate MRI use increased substantially across US hospitals between 2017 and 2026, reflecting broader uptake of guideline-supported imaging, although a substantial proportion of patients still undergo biopsy without MRI evaluation.

A patient with PNH and persistent anemia during ravulizumab therapy experienced improved hemoglobin after danicopan was added, while an extended infusion delay highlighted treatment-continuity challenges without establishing protection from interrupted C5 inhibition.

An experimental cell therapy that couples a patient’s red blood cells with myelin protein fragments was well tolerated in a 10-patient Phase 1b study and was associated with increases in regulatory T-cells and reductions in neurofilament light chain, a biomarker linked to nerve injury.