Articles related to CLINICAL STUDY

An 8-week observational study of young adults with acne found significant improvements in both acne severity and dermatology-related quality of life. Improvements in clinical grading did not correlate with patient-reported quality-of-life gains, highlighting the multidimensional impact of acne.

Prenatal fish oil supplementation was associated with small differences in cerebral blood flow and oxygen metabolism at age 10. Cognitive and psychopathology outcomes showed no significant association.

A phase 2b trial found that biweekly bofanglutide significantly reduced HbA1c levels and produced weight loss in adults with type 2 diabetes. The findings add to ongoing development of longer-interval GLP-1 therapies, though larger and longer studies remain necessary.

A plasma p-tau217/Aβ42 ratio accurately identified amyloid-PET positivity in older veterans without traumatic brain injury, but diagnostic performance declined substantially among those with a history of TBI, particularly following more severe injuries.

PrimeC lowered neuron-derived TDP-43 levels in a Phase 2b ALS trial, with earlier analyses reporting functional and survival signals requiring confirmation in a planned pivotal study.

Six weeks of moderate sleep restriction increased weight, waist circumference, and sedentary time in adults with baseline adequate sleep and elevated cardiometabolic risk.