Articles related to MENOPAUSE

Proteomic analysis of normal ovaries from 28 postmenopausal women identified age-associated differences in inflammation and tissue remodeling. The findings describe molecular activity, not restored fertility, and do not establish cancer risk or benefits from ovarian removal.

Psychological menopause symptoms were associated with greater intention to leave employment in a Japanese cross-sectional study of more than 1,600 working women. Conference-reported findings do not establish causality or document actual workforce departures.

Mayim Bialik reports prolonged gastrointestinal symptoms after one dose of an unnamed GLP-1 medication taken for autoimmune symptoms. Her account describes individual intolerance, not the frequency of severe reactions or evidence of autoimmune benefit.

ACP places estrogen-based therapy first in its pharmacologic pathway for menopausal vasomotor symptoms, with nonhormonal alternatives for contraindications or intolerance. Recommendation strength and evidence certainty vary, and long-term safety evidence remains limited.

A large Danish registry study found that current use of oral menopausal hormone therapy was associated with increased venous thromboembolism risk, while transdermal therapy was not generally associated with higher thrombotic rates across regimens, doses, or durations.

Testosterone prescribing for women has risen sharply despite the absence of FDA-approved female-specific products. The increase is occurring alongside pharmacy dispensing barriers and renewed regulatory attention, while guideline-supported use remains largely limited to hypoactive sexual desire disorder in postmenopausal women.