Articles related to PHARMACOTHERAPY

“Additional research is needed to determine whether the modest elevations in suicidal behavior observed during treatment are due to true medication effects or to persistence in the distress that prompted treatment initiation.” — Study authors, Biological Psychiatry Global Open Science

Reductions in lean body mass are likely concentrated in non-contractile components rather than reflecting a clear decline in muscle function.

“There is enormous exuberance about starting GLP-1 drugs, but not nearly enough attention to what happens when people stop.” – Senior study author Ziyad Al-Aly, MD; Washington University School of Medicine

The approval was based on data from the randomized, double-blinded, parallel-group phase 3b STEP UP trial, which enrolled 1407 adults aged 18 years and older with a body mass index of at least 30kg/m2, without diabetes.

“People who maintain low levels of LDL-C and triglycerides at earlier ages are much less likely to develop atherosclerotic disease decades later.” — Pamela B. Morris, MD, FACC, FAHA, guideline writing committee vice-chair

“A fully oral, inexpensive NMDA-AMPA modulation strategy may offer a practical alternative for patients with the bipolar obsessive-compulsive disorder phenotype who respond poorly to conventional approaches.” — Ngo Cheung, MBBS