Articles related to Cardiology

A European Heart Journal debate revisits whether surgical aortic valve replacement should remain the preferred approach for patients with aortic stenosis and life expectancy beyond five years. Long-term durability and late procedural outcomes continue to shape the discussion.

Among more than 117,000 women followed in two Nurses’ Health Study cohorts, greater resistance-training participation was associated with lower rates of major cardiovascular disease. Risk reductions were most pronounced when strength training was paired with aerobic exercise.

A new ACC scientific statement summarizes current evidence for antiplatelet therapy across primary prevention, ACS, PCI, CAD, and PAD management. The document emphasizes individualized assessment of ischemic and bleeding risks.

The FDA approved enlicitide, the first oral PCSK9 inhibitor, after phase 3 studies demonstrated substantial LDL-C reductions in patients requiring additional lipid lowering. Cardiovascular outcomes data remain pending.

Premature menopause was linked to a 40% higher long-term risk of coronary heart disease in a pooled analysis of more than 10,000 women followed across six cohort studies.

The FDA approved olezarsen (Tryngolza), an apoC-III antisense inhibitor, as an adjunct to diet for reducing triglycerides and acute pancreatitis risk in adults with severe hypertriglyceridemia, based on phase 3 data showing an 85% reduction in pancreatitis events compared with placebo.