Articles related to Physical Medicine & Rehabilitation

A joint epilepsy society position statement endorsed validated noninvasive seizure detection and alerting devices as part of individualized epilepsy care while emphasizing their strongest performance in tonic-clonic seizures and the absence of proven SUDEP prevention.

PrimeC lowered neuron-derived TDP-43 levels in a Phase 2b ALS trial, with earlier analyses reporting functional and survival signals requiring confirmation in a planned pivotal study.

Differences in cerebrospinal fluid proteins distinguished women with multiple sclerosis from age-matched controls in a small exploratory study, highlighting potential hormonal and immune-related biological mechanisms. Findings require validation in larger populations before clinical application.

A network meta-analysis of 32 randomized trials found long-term, high-dose vitamin D supplementation added to standard multiple sclerosis therapy reduced relapse risk and eased disability progression, while short-term use showed no significant effect.

A decade after surgery, patients who got their torn meniscus trimmed fared worse than those who received a sham procedure. The sham group reported less pain, more knee use, and less arthritis progression.

Preclinical findings point to a potential role for extracellular vesicles in cartilage repair, offering insight into future directions for osteoarthritis research.