Articles related to RISK FACTORS

A large Danish registry study found that current use of oral menopausal hormone therapy was associated with increased venous thromboembolism risk, while transdermal therapy was not generally associated with higher thrombotic rates across regimens, doses, or durations.

Fetal macrosomia showed the strongest association with shoulder dystocia in a single-center case-control study of vaginal deliveries. Maternal overweight and diabetes also contributed to risk, while the low event count and retrospective design limit prediction.

Higher circulating xylitol levels were associated with increased rates of major adverse cardiovascular events in two large population cohorts, although the observational findings do not establish that xylitol directly causes cardiovascular harm.

Among nearly 1 million UK adults, preference for very hot beverages and consumption of at least six hot drinks daily were associated with higher esophageal squamous cell carcinoma risk, but not materially with adenocarcinoma.

A report examining a celebrity-backed sports prediction campaign highlights concerns about increasing youth exposure to gambling-related marketing. The article connects growing gambling participation among adolescents and young adults with evidence linking gambling disorder to adverse mental health outcomes, including suicidality.

In a propensity-matched analysis of more than 66,000 adults with hypertension, blood-brain barrier (BBB)-crossing antihypertensives were associated with a 16% lower dementia risk than BBB-non-crossing agents. The observational design prevents causal conclusions but adds to growing interest in whether some antihypertensives may influence cognitive outcomes beyond blood pressure control.