Articles related to COGNITIVE HEALTH/MEMORY

Frontal release sign positivity was associated with a 78% higher hazard of developing dementia among cognitively intact adults aged 70 and older in a longitudinal cohort study at a single academic Alzheimer’s research center.

Multimodal MRI analysis identified two distinct migraine subgroups in a 111-patient cohort, with one cluster showing widespread cortical-subcortical connectivity changes and lower cortical volumes tied to greater disease burden and disability.

Glucosamine use was associated with a 25% increase in mortality risk in patients with Alzheimer’s disease-related dementia in a retrospective analysis of more than 50,000 patients, with no corresponding signal observed in those with mild cognitive impairment.

A 509,926-patient Medicare cohort found that recombinant herpes zoster vaccination was associated with a 5.8 percentage point reduction in 4-year dementia risk among older adults following skilled-nursing facility admission, adding to a growing body of observational evidence linking RZV to cognitive protection.

Sleep midpoint variability, duration variability, and social jetlag were each associated with lower receptive vocabulary and visuospatial memory scores in 379 preschool-age children, with executive attention unaffected by any sleep regularity measure.

Accelerometer-derived sleep-wake cycle metrics independently predicted incident dementia in 53,448 UK Biobank participants, with predictive improvement comparable to APOE genotype contribution when added to age-only models.