Articles related to HEALTH OUTCOMES

Among more than 7,300 Swedish patients with Alzheimer’s disease and atrial fibrillation, NOAC use was associated with slower cognitive decline than warfarin or no anticoagulation. The observational findings did not establish causality but suggest potential differences in long-term cognitive outcomes.

A mathematical modeling study estimated that somatic DNA mutations alone could limit median human life span to roughly 146 to 194 years. The findings add to ongoing research suggesting that aging reflects multiple interacting biological processes rather than a single mechanism.

Across 14 health-system specialty pharmacies, pharmacist interventions were associated with an estimated $3.6 million in avoided medication costs over six months. The analysis used a structured attribution method to assess the likelihood that individual interventions altered treatment trajectories.

A national analysis found that clinical obesity was present in more than one-quarter of adults with normal BMI values. The findings highlight limitations of BMI alone for identifying excess adiposity and obesity-related health risk.

More than half of women aged 50–80 reported sleep problems in a cross-sectional survey analysis, with symptomatic menopausal women significantly more likely to be affected than those without menopausal symptoms.

Algorithm-guided treatment was associated with improved remission rates in 5 of 7 randomized trials of major depressive disorder, though heterogeneity in protocols and outcome measures limited direct comparability.