Articles related to COHORT STUDY

Systemic nicotinamide exposure was associated with a lower risk of conversion from ocular hypertension to primary open-angle glaucoma in a large real-world cohort. Patients receiving nicotinamide also had lower rates of topical therapy initiation and laser trabeculoplasty, although the study did not establish causality.

In an observational target trial emulation of patients with atrial fibrillation and mitral stenosis, DOACs were associated with higher 1-year stroke risk than warfarin. Bleeding and all-cause mortality risks did not differ between groups.

Two prospective cohorts found that metabolically unhealthy adults generally had higher dementia risk estimates regardless of obesity status. Metabolically healthy obesity was not associated with increased dementia risk in primary analyses, though findings varied across sensitivity analyses.

A Swedish register-based cohort associated GLP-1 receptor agonist use with higher relative risk of anterior ischemic optic neuropathy. Absolute event rates were low, and findings attenuated after diabetes-severity controls.

Video-based ADHD prescribing increased substantially following Australia’s permanent telehealth reforms, with ADHD consultations showing greater virtual adoption than other psychotropic prescribing categories. Observational findings describe utilization patterns but do not establish causality.

Filtered coffee consumption was associated with lower biological age-acceleration measures in nearly 50,000 UK Biobank participants, while instant coffee showed the opposite pattern. The cross-sectional analysis did not establish causality and remains hypothesis-generating.